Photodynamic Therapy (PDT): PDT Mechanisms

By R. Allison, K. Moghissi. Clinical Endoscopy, 2013

604 citations recorded by the source corpus.

Photodynamic therapy (PDT) is a light based therapy used to ablate tumors. As practiced in oncology a photosensitizing agent is applied and then activated by a specific wavelength and energy of light. This light energy in the presence of oxygen will lead to the creation of the photodynamic reaction which is cyto and vasculo toxic. This paper will review the mechanisms of action of PDT and how they may be manipulated to improve clinical outcome in cancer patients.

Subfields: Biomedical Engineering, Cancer Research, Pulmonary and Respiratory Medicine

View Paper: https://www.semanticscholar.org/paper/f67558443f248c90f743e0a5df54c21ec799c999

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In Biomedical Engineering

1. Zhaochu Yang
2. Tao Dong

Citations in the corpus

• Photodynamic Therapy Review: Principles, Photosensitizers, Applications, and Future Directions (2021, background): “Tumor destruction from PDT can occur by both programmed (apoptotic) pathways and non-programmed (necrosis) pathways [11,16].”