Oscillatory nature of human basal ganglia activity: Relationship to the pathophysiology of Parkinson's disease

By Peter Brown. Movement Disorders, 2003

1,021 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience, Neurology

View Paper: https://www.semanticscholar.org/paper/f6676c9f5f7e15c8e43921e341f1ef460126a155

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Citations in the corpus

Oscillations and the basal ganglia: Motor control and beyond (2013, neutral): “gamma activity), based on their respective behavioural associations in patients with PD (Brown, 2003).”
Abnormal intrinsic brain functional network dynamics in Parkinson’s disease (2017, background): “, 2007), reported to be associated with motor impairment in Parkinson’s disease (Brown, 2003; Silberstein et al., 2005; Stoffers et al., 2008; Hammerer and Eppinger, 2012).”
Normal and pathological oscillatory communication in the brain (2005, background): “For example, an abnormal pattern of synchronization in parts of the motor system seems to be a key pathophysiological mechanism that underlies motor symptoms, such as tremor and poverty of movement, in Parkinson's diseas”
High-Frequency Stimulation of the Subthalamic Nucleus Suppresses Oscillatory β Activity in Patients with Parkinson's Disease in Parallel with Improvement in Motor Performance (2008, neutral): “The HFS-induced effect on activity is similar to that observed after levodopa treatment in PD (Priori et al., 2004) and would be in line with the notion that enhanced activity is antikinetic and may contribute to the pathophysiology of Parkinson’s disease (Brown, 2003; Brown and Williams, 2005).”
Self-paced movements induce high-frequency gamma oscillations in primary motor cortex (2008, background): “There is evidence that direct projections from MI to the 5 STN mediate both beta and low gamma oscillatory activity within 5 cortical–basal ganglia loops (Brown, 2003) and a recent study”
Event-related beta desynchronization in human subthalamic nucleus correlates with motor performance. (2004, background): “That motor programming is associated with a reduction in the degree of synchronization in the beta band within STN is in accord with the hypothesis that this activity may be considered antikinetic in nature (Brown, 2003).”
Beta-band oscillations--signalling the status quo? (2010, neutral): “Panels (a) and (b) modified with permission from [65].”
Closed-loop deep brain stimulation is superior in ameliorating parkinsonism. (2011, neutral): “Indeed, both the neuronal discharge of the BG in PD patients and MPTP-treated primates and the parkinsonian motor symptoms display considerably faster dynamics than those provided by the adjustments of DBS therapy (Brown, 2003; Deuschl et al., 2006; Hammond et al., 2007; Moro et al., 2006; Raz et al”
Reduction in subthalamic 8–35 Hz oscillatory activity correlates with clinical improvement in Parkinson's disease (2006, background): “The present demonstration of a strong positive correlation between the reduction in peak 8–35 Hz LFP power in the STN after levodopa therapy and improvement in UPDRS following levodopa further supports the hypothesis that a pathological synchronization of neuronal activity in this frequency range co”
Oscillations in the Basal Ganglia: The good, the bad, and the unexpected (2005, background): “In particular, after treatment with dopamine agonists or the dopamine precursor, levodopa, some PD patients develop a new pattern of LFP oscillation at 65-85 Hz (Brown et al., 2001; Cassidy et al., 2002; Williams et al., 2002; Brown, 2003).”