Endocannabinoid signaling as a synaptic circuit breaker in neurological disease

By I. Katona, Tamás F. Freund. Nature Medicine, 2008

594 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience, Pharmacology

View Paper: https://www.semanticscholar.org/paper/f600bb543b030bc678d638d52d2959772f8433bb

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. O. Marín
2. U. Kumar
3. Shenglong Zou

In Cognitive Neuroscience

1. P. Goadsby
2. O. Marín
3. U. Kumar
4. Shenglong Zou

In Pharmacology

1. O. Marín
2. U. Kumar
3. Shenglong Zou

Citations in the corpus

• Pathophysiology of Migraine: A Disorder of Sensory Processing. (2017, background): “Endocannabinoids are described as “synaptic circuit-breakers” (459) acting as retrograde neurotransmitters in the PAG and RVM.”
• Interneuron dysfunction in psychiatric disorders (2012, background): “Activation of CB1 suppresses GABA release from synaptic terminals of CCK-expressing (CCK + ) interneuron cell”
• Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System (2018, background): “Given these facts, it is proposed that 2-AG is the primary endogenous ligand for CBRs in the central nervous system (CNS) [32,34,35].”