Reading, writing and erasing mRNA methylation

By S. Zaccara, R. Ries, Samie R. Jaffrey. Nature reviews. Molecular cell biology, 2019

2,081 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/f4f0bf70980060460a7fd78dd9369576a16d1185

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. S. Zaccara
2. Samie R. Jaffrey
3. Chuan He
4. P. He
5. Kate D. Meyer

Citations in the corpus

• A Unified Model for the Function of YTHDF Proteins in Regulating m6A-Modified mRNA (2020, background): “However, since eIF3 and METTL3 are thought to bind just a small subset of m6A sites, the role of eIF3 and METTL3 binding in the overall cellular effects of m6A is likely to be limited to specific transcripts (Zaccara et al., 2019).”
• Functions of N6-methyladenosine and its role in cancer (2019, background): “Research aimed at uncovering the mechanism has shown that m6A serves as a regulator in cancer [156, 157].”
• Regulatory mechanisms of PD-1/PD-L1 in cancers (2024, background): “This post-transcriptional m 6 A modification of RNA is dynamically reversible, mainly involving three types of regulatory factors, methyltrans-ferases (writers), demethylases (erasers), and m6A-bind-ing proteins (readers) [263].”
• Circular RNA: metabolism, functions and interactions with proteins (2020, background): “M6A is the most common RNA modification and is regulated by readers, writers and erasers [61].”