Overt and Subclinical Hypothyroidism Complicating Pregnancy

By M. Abalovich, S. Gutiérrez, G. Alcaraz, G. Maccallini, Andrea Garcia, O. Levalle. Thyroid, 2002

726 citations recorded by the source corpus.

Subfields: Endocrinology, Diabetes and Metabolism, Public Health, Environmental and Occupational Health

View Paper: https://www.semanticscholar.org/paper/f4bd2e421932ef7f2ac5fd89af5d7c369f0e06d9

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In Endocrinology, Diabetes and Metabolism

G. Brent

Citations in the corpus

Guidelines for the Treatment of Hypothyroidism: Prepared by the American Thyroid Association Task Force on Thyroid Hormone Replacement (2014, neutral): “Overt hypothyroidism (OH) is associated with an increased rate of maternal complications, including decreased fertility, increased miscarriage or stillbirth, hypertension, and postpartum hemorrhage (269,270).”
Levothyroxine treatment in euthyroid pregnant women with autoimmune thyroid disease: effects on obstetrical complications. (2006, background): “• LT4 in Autoimmune Thyroid Disease during Pregnancy J Clin Endocrinol Metab, July 2006, 91(7):2587–2591 2589”
Management of thyroid dysfunction during pregnancy and postpartum: an Endocrine Society clinical practice guideline. (2007, background): “Although the majority of large-scale, well-designed studies depict a consistent adverse impact from mild to moderate maternal hypothyroidism, some studies are contradictory (9, 80).”
Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and Postpartum (2011, background): “(38) demonstrated such patients carry an estimated 60% risk of fetal loss when OH was not adequately detected and treated.”
2017 Guidelines of the American Thyroid Association for the Diagnosis and Management of Thyroid Disease During Pregnancy and the Postpartum (2011, background): “While prior retrospective studies have suggested a benefit of LT4 treatment in this population (276,277), such findings have not been sufficiently replicated in blinded, prospective analyses thus far.”