The well-worn route and the path less traveled: distinct neural bases of route following and wayfinding in humans.

By T. Hartley, Eleanor A. Maguire, Hugo J. Spiers, Neil Burgess. Neuron, 2003

859 citations recorded by the source corpus.

Subfields: Automotive Engineering, Cognitive Neuroscience, Developmental and Educational Psychology

View Paper: https://www.semanticscholar.org/paper/f4221d3e0a72a4476419944c30e341a5e4b33723

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In Automotive Engineering

In Cognitive Neuroscience

In Developmental and Educational Psychology

Citations in the corpus

London taxi drivers and bus drivers: A structural MRI and neuropsychological analysis (2006, background): “…functional MRI (fMRI) that repeatedly following a single short route can lead to activation of the caudate nucleus rather than the hippocampus (Hartley et al., 2003; Iaria et al., FIGURE 1 Hippocampus DOI 10.1002/hipo 2003; Voermans et al., 2004; and in nonhumans Packard and McGaugh, 1996;…”
The neuroscience of remote memory. (2007, background): “Importantly, activity in the parahippocampal cortex, and sometimes also in the hippocampus, occurred when volunteers learned new routes [56,57].”
Vestibular loss causes hippocampal atrophy and impaired spatial memory in humans. (2005, background): “, 1997, 1998) or fMRI scanning (Grön et al., 2000; Hartley et al., 2003), showed activation of especially the right hippocampus in wayfinding, a navigation task defined as ‘finding novel paths between locations’, mainly when the subjects used spatial landmarks to navigate in the early phase of a pla”
Using imagination to understand the neural basis of episodic memory (2007, background): “…other high-level cognitive functions including future thinking (Addis et al., 2007; Szpunar et al., 2007), spatial navigation (Burgess et al., 2002; Hartley et al., 2003), theory of mind (Frith and Frith, 2003), the default network (Raichle et al., 2001), and perhaps even daydreaming (Mason et…”
Using Grid Cells for Navigation (2015, background): “Similarly, metabolic activity in the human hippocampus correlates with navigational performance (Maguire et al., 1998; Hartley et al., 2003; Iaria et al., 2003), and damage to the hippocampus is associated with impaired spatial navigation (Kolb and Whishaw, 1996; Abrahams et al.”
Place cells, grid cells, and the brain's spatial representation system. (2008, background): “Finally, it is possible that navigation can be aided also by action-based neural computations in the striatum, where key positions along the trajectory are reflected in the local activity ( Jog et al. 1999; see also Packard & McGaugh 1996, Hartley et al. 2003).”
Hippocampal Amnesia Impairs All Manner of Relational Memory (2008, background): “Neuroimaging data collected during performance of spatial tasks almost universally reveal MTL activation, frequently in hippocampus and parahippocampal cortex (e.g., Hartley et al., 2003; Pine et al., 2002; Spiers and Maguire, 2006).”
Maze training in mice induces MRI-detectable brain shape changes specific to the type of learning (2011, background): “The importance of the hippocampus and striatum in spatial and response learning respectively has been well established (McDonald and White, 1994; Devan et al., 1996; Korol and Kolo, 2002; Colombo et al., 2003; Gold, 2003; Hartley et al., 2003; Iaria et al., 2003; Bohbot et al., 2007; Doeller et al.,”
Functional neuroanatomy of remote episodic, semantic and spatial memory: a unified account based on multiple trace theory (2005, result): “The results of our studies on remote spatial memory, like those of Burgess, Maguire and their collaborators (Burgess, 2002; Burgess et al. 2002; Hartley et al. 2003) on anterograde spatial memory, suggest that remote spatial and episodic memory have much in common, though we differ in our conception”