American Society of Hematology 2018 guidelines for management of venous thromboembolism: prophylaxis for hospitalized and nonhospitalized medical patients.
By Holger J. Schünemann, M. Cushman, Allison E. Burnett, S. Kahn, J. Beyer-Westendorf, F. Spencer, S. Rezende, N. Zakai, K. Bauer, F. Dentali and 9 more. Blood Advances, 2018
665 citations recorded by the source corpus.
BACKGROUND Venous thromboembolism (VTE) is the third most common vascular disease. Medical inpatients, long-term care residents, persons with minor injuries, and long-distance travelers are at increased risk. OBJECTIVE These evidence-based guidelines from the American Society of Hematology (ASH) intend to support patients, clinicians, and others in decisions about preventing VTE in these groups. METHODS ASH formed a multidisciplinary guideline panel balanced to minimize potential bias from conflicts of interest. The McMaster University GRADE Centre supported the guideline-development process, including updating or performing systematic evidence reviews. The panel prioritized clinical questions and outcomes according to their importance for clinicians and adult patients. The Grading of Recommendations Assessment, Development and Evaluation approach was used to assess evidence and make recommendations, which were subject to public comment. RESULTS The panel agreed on 19 recommendations for acutely ill and critically ill medical inpatients, people in long-term care facilities, outpatients with minor injuries, and long-distance travelers. CONCLUSIONS Strong recommendations included provision of pharmacological VTE prophylaxis in acutely or critically ill inpatients at acceptable bleeding risk, use of mechanical prophylaxis when bleeding risk is unacceptable, against the use of direct oral anticoagulants during hospitalization, and against extending pharmacological prophylaxis after hospital discharge. Conditional recommendations included not to use VTE prophylaxis routinely in long-term care patients or outpatients with minor VTE risk factors. The panel conditionally recommended use of graduated compression stockings or low-molecular-weight heparin in long-distance travelers only if they are at high risk for VTE.
Subfields: Biomedical Engineering, Emergency Medicine, Internal Medicine
View Paper: https://www.semanticscholar.org/paper/ab9e5cbe7524406cfaaf64c06cf8240a4f8859a6
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Citations in the corpus
- American Society of Hematology 2021 guidelines for management of venous thromboembolism: prevention and treatment in patients with cancer. (2021, methodology): “Because of a lack of direct evidence, the guideline panel also included evidence from trials conducted on hospitalized medical patients from the 2018 ASH guidelines for management of VTE on prophylaxis for hospitalized and nonhospitalized medical patients.(59)”
- European Resuscitation Council and European Society of Intensive Care Medicine Guidelines 2021: Post-resuscitation care. (2021, background): “Thus, treatment should be individualised and be based on general ICU recommendations [277].”
- COVID-19 and Thrombotic or Thromboembolic Disease: Implications for Prevention, Antithrombotic Therapy, and Follow-Up (2020, background): “The choice of agents and dosing should be based on available guideline recom mendations (53,54,63).”