Manganese Increases the Sensitivity of the cGAS‐STING Pathway for Double‐Stranded DNA and Is Required for the Host Defense against DNA Viruses
By Chenguang Wang, Yukun Guan, Mengze Lv, Rui Zhang, Zhaoying Guo, Xiaoming Wei, Xiaoxia Du, Jing Yang, Tong Li, Y. Wan and 3 more. Immunity, 2018
733 citations recorded by the source corpus.
Subfields: Immunology, Infectious Diseases, Public Health, Environmental and Occupational Health
View Paper: https://www.semanticscholar.org/paper/f2e95d6d9aea7a2d6aa047b7c616c5d4ca4aaabb
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- Kongming Wu
- Ming Yi
- Xiaoli Zheng
- Mengke Niu
- Xuemei He
- Yu-long Cai
- Shuangli Zhu
- Yuquan Wei
Citations in the corpus
- Combination strategies with PD-1/PD-L1 blockade: current advances and future directions (2022, background): “Besides, manganese is also identified as a natural STING agonist, playing an important role in antitumor immunity [270, 271].”
- Vaccine adjuvants: mechanisms and platforms (2023, background): “In this way, manganese activates the innate immune pathway of cGAS-STING, induces the production of type I interferons, enhances antigen presentation and cross-presentation, promotes the production of antibodies and increases the production of CD8 T cell immune responses.(252,253) It is reported tha”