Ascorbic acid and reproduction in fish: endocrine regulation and gamete quality
By K. Dąbrowski, A. Ciereszko. 2001
87 citations recorded by the source corpus.
High ascorbic acid concentrations have been associated with gonad and brain tissues in teleost fishes. Although a direct dietary effect on gamete quality has been given some attention recently, the mechanism of action of ascorbate along the cascade of reproductive events in the hypothalamus, pituitary and gonads has not been defined. Data relating to gamete production and quality, as well as a possible protective role for ascorbate against cumulative genetic defects during gametogenesis and congenital malformation during gestation (embryonic development) is reviewed. It is suggested that the gonad growth in response to gonadotropin stimulation involves direct interaction between catecholamines and steroid hormones and their receptor sites. This interaction acts as a regulatory mechanism of ascorbate absorption, transfer and metabolism (degradation and/or renewal) in the reproductive system. We conclude that ascorbic acid is a leading nutrient in reproductive tissue functions and further research is needed on: (1) its antioxidant effect on gametes' (sperm and ova) capacity to prevent DNA damage occurring prior to (endogenous) and after spawning (environmental insults); (2) its dietary requirement to optimize survival and physiological recovery in multiple spawners; (3) the integration mechanism of ascorbic acid action as part of the overall endocrine regulation of neurohormonal–hormonal pathway in fish reproduction; and (4) the possible role for ascorbate in regulating fish maturation and/or infertility in the presence of enhanced UV-radiation or conditions of intensive aquaculture (hypoxia, oxygen supersaturation, dietary pro–, and antioxidants).
Subfields: Aquatic Science, Biochemistry, Physiology
View Paper: https://www.semanticscholar.org/paper/f2d7ee2958e6424f7858aa26cd44cf47905a2fb4
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In Aquatic Science
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Citations in the corpus
- Development of Captive Breeding Techniques for Marine Ornamental Fish: A Review (2010, background): “…highly unsaturated fatty acids (HUFA), vitamin E, vitamin C, and carotenoids (Sandnes, 1984; Ciereszko and Dabrowski, 1995, 2000; Bell et al., 1996; Dabrowski and Ciereszko, 1996, 2001; Asturiano et al., 2001; Izquierdo et al., 2001; Coward et al., 2002; Watanabe and Vassallo-Agius, 2003;…”