mRNA-lipid nanoparticle COVID-19 vaccines: Structure and stability

By L. Schoenmaker, D. Witzigmann, J. Kulkarni, Rein Verbeke, G. Kersten, W. Jiskoot, D. Crommelin. International journal of pharmaceutics, 2021

1,255 citations recorded by the source corpus.

Graphical abstract

Subfields: Animal Science and Zoology, Infectious Diseases, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/f1edf6b29d31011095094c11c92f6df778b72cb8

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In Molecular Biology

1. Michael J. Hogan
2. N. Pardi

Citations in the corpus

• mRNA Vaccines in the COVID-19 Pandemic and Beyond. (2021, background): “It is plausible that the stability differs due to the distinct lipid composition or to the different excipients added to the vials (113).”
• The role of lipid components in lipid nanoparticles for vaccines and gene therapy (2022, neutral): “We do know the LNP structure in a specific formulation highly depends on the molecular structure of the lipid components, lipid composition, type of cargo, and intraparticle heterogeneity [13].”