Proteome survey reveals modularity of the yeast cell machinery

By A. Gavin, Patrick Aloy, P. Grandi, R. Krause, Markus Boesche, M. Marzioch, Christina E. Rau, Lars Juhl Jensen, Sonja Bastuck, Birgit Dümpelfeld and 22 more. Nature, 2006

2,700 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/f13b18f27794bebd7852a1b56810f17b8b081f8a

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Citations in the corpus

Yeast Two-Hybrid, a Powerful Tool for Systems Biology (2009, positive): “With the TAP-tag approach, Gavin et al. [36,37] and Krogan et al. [38] purified 1,993 and 2,357 TAP-fusion proteins covering 60% and 72% of the yeast proteome, respectively.”
clusterMaker: a multi-algorithm clustering plugin for Cytoscape (2011, methodology): “This data set combines three previously published high-throughput protein interaction data sets [35,50,51] to increase the quality and coverage of the resulting interaction network.”
Determining the stoichiometry and interactions of macromolecular assemblies from mass spectrometry (2007, methodology): “The development of epitope tagging and affinity purification techniques, performed under native conditions, has produced vast networks of protein interaction”
Exploring genetic interactions and networks with yeast (2007, methodology): “or affinity purification followed by mass spectrometry identificatio”
Global landscape of HIV–human protein complexes (2011, background): “b, Western blot of HEK293 cell lysate expressing FLAG-tagged eIF3 subunits in the absence (2) or presence (1) of active PR probed with an anti-FLAG antibody.”
Docking and scoring protein interactions: CAPRI 2009 (2010, background): “The docking community currently recognizes three main aspects that need addressing: (1) improving the criteria for singling out promising solutions, (2) modeling conformational changes, and (3) incorporating restraints on the basis of data from different sources.”
Semi-supervised multi-task learning for predicting interactions between HIV-1 and human proteins (2010, methodology): “…et al., 2005; Stelzl et al., 2005; Uetz et al., 2000) and complex ∗To whom correspondence should be addressed. purification detection techniques using mass spectrometry (Gavin et al., 2002, 2006; Ho et al., 2002) are the two most popular approaches thus far applied successfully on a large scale .”
Where Have All the Interactions Gone? Estimating the Coverage of Two-Hybrid Protein Interaction Maps (2007, background): “A constant proviso attached to interaction screens is the suspicion that methods such as two-hybrid screens, affinity pull-downs [56,57], and protein binding chips [58] will identify different subsets of interactions.”
Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins. (2006, background): “It was also detected as a partner of Hrd1p in recent proteomic experiments (Gavin et al., 2006).”
Link communities reveal multiscale complexity in networks (2009, background): “6,7,9,10,14,15 Pervasive overlap in real networks is distinct from ‘fuzzy’ community overlap with relaxed interfaces, 19–21 because overlap can exist for each and every node (Fig.”