Amphetamine, 3,4-methylenedioxymethamphetamine, lysergic acid diethylamide, and metabolites of the catecholamine neurotransmitters are agonists of a rat trace amine receptor.
By J. Bunzow, M. Sonders, S. Arttamangkul, L. Harrison, Ge Zhang, D. Quigley, T. Darland, K. Suchland, Shailaja Pasumamula, James L. Kennedy and 4 more. Molecular Pharmacology, 2001
643 citations recorded by the source corpus.
Subfields: Cellular and Molecular Neuroscience, Clinical Psychology, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/f0df93e2f01de63c38a6d1d85f74feee4b2a2c1c
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Citations in the corpus
- Mechanisms of neurotransmitter release by amphetamines: a review. (2005, background): “There has been a resurgence in interest in this topic due to the discovery of a family of 15 mammalian G protein-coupled trace amine receptors (Borowsky et al., 2001; Bunzow et al., 2001).”
- The Pharmacology and Clinical Pharmacology of 3,4-Methylenedioxymethamphetamine (MDMA, “Ecstasy”) (2003, background): “In addition to these classical receptors, MDMA has recently been reported to possess high affinity (EC50 1.7 M) and efficacy for a novel receptor that is positively coupled to adenylyl cyclase, for which the endogenous agonist may be a trace amine such as tyramine (Bunzow et al., 2001).”
- Monoamine oxidase inactivation: from pathophysiology to therapeutics (2008, background): “It is not surprising that the phenotypical alterations observed so far in MAO B KO mice are more subtle than those in MAO A KO mice, since PEA is present in very small concentrations in the brain [66,67] and is thought to serve amphetamine-like functions in the modulation of the neurotransmission an”