Pro-oxidant and cytotoxic effects of circulating heme.

By V. Jeney, J. Balla, A. Yachie, Z. Varga, G. Vercellotti, J. Eaton, G. Balla. Blood, 2002

648 citations recorded by the source corpus.

Subfields: Cell Biology, Critical Care and Intensive Care Medicine, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/f09f7f4ec70bf7396dc22008be7ade32b12839b0

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In Molecular Biology

1. Rui Wang
2. Lingyun Wu
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Citations in the corpus

• Mechanisms of cell protection by heme oxygenase-1. (2010, background): “However, based on the cytotoxic effects of oxidized LDL or HDL, in particular to endothelial cells (217), it is possible that heme-assisted LDL or HDL oxidation might promote the pathogenesis of some vascular diseases, such as lipid-mediated atherosclerosis, an effect that would explain the protecti”
• Carbon Monoxide: Endogenous Production, Physiological Functions, and Pharmacological Applications (2005, background): “Free heme at high concentrations catalyzes oxidative reactions to generate reactive oxygen species (Jeney et al., 2002), mainly due to the catalytic effect of heme.”