An overview of microRNAs

By Scott M. Hammond. Advanced Drug Delivery Reviews, 2015

1,273 citations recorded by the source corpus.

The discovery of the first microRNA (miRNA) over 20 years ago has ushered in a new era in molecular biology. There are now over 2000 miRNAs that have been discovered in humans and it is believed that they collectively regulate one third of the genes in the genome. miRNAs have been linked to many human diseases and are being pursued as clinical diagnostics and as therapeutic targets. This review presents an overview of the miRNA pathway, including biogenesis routes, biological roles, and clinical approaches.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/f01c2213e56aae557faea605e7d061213984457e

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In Cancer Research

1. H. K. Khorram Khorshid
2. K. Saliminejad
3. S. Ghaffari
4. Shahrzad Soleymani Fard

In Molecular Biology

1. H. K. Khorram Khorshid
2. K. Saliminejad
3. S. Ghaffari
4. Shahrzad Soleymani Fard

Citations in the corpus

• An overview of microRNAs: Biology, functions, therapeutics, and analysis methods (2018, background): “Uncovering the biological function of individual miRNAs is usually performed by animal knockout models and transgenic overexpression experiments (Hammond, 2015).”