Designer emulsions using microfluidics
By R. K. Shah, H. Shum, A. Rowat, Daeyeon Lee, J. Agresti, A. Utada, L. Chu, Jin-woong Kim, A. Fernández-Nieves, C. Martinez and 1 more. 2008
685 citations recorded by the source corpus.
We describe new developments for the controlled fabrication of monodisperse emulsions using microfluidics. We use glass capillary devices to generate single, double, and higher order emulsions with exceptional precision. These emulsions can serve as ideal templates for generating well-defined particles and functional vesicles. Polydimethylsiloxane microfluidic devices are also used to generate picoliter-scale water-in-oil emulsions at rates as high as 10 000 drops per second. These emulsions have great potential as individual microvessels in high-throughput screening applications, where each drop serves to encapsulate single cells, genes, or reactants.
Subfields: Biomedical Engineering, Electrical and Electronic Engineering
View Paper: https://www.semanticscholar.org/paper/efa734f8b3a14ee2fb4cd9b01c3bbfe69add12ba
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In Biomedical Engineering
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Citations in the corpus
- Production of uniform droplets using membrane, microchannel and microfluidic emulsification devices (2012, background): “Under dripping regime, monodisperse drops are formed at the tip of the injection capillary (Shah et al., 2008).”
- Microfluidic Production of Multiple Emulsions (2017, background): “A significant advantage of glass capillaries is the straightforward control over their wettability by a surface reaction with an appropriate silane coupling agent [55].”
- Porous Polymer Particles - A Comprehensive Guide to Synthesis, Characterization, Functionalization and Applications (2012, methodology): “In the case of W/O emulsions, the glass capillary device needs to be adapted which can be easily done via chemical treatment by silanes [214].”
- Small but Perfectly Formed? Successes, Challenges, and Opportunities for Microfluidics in the Chemical and Biological Sciences (2017, background): “Even more sophisticated microstructures can be formed by forcing droplets into other droplets to make designer double or triple emulsions.(101) Select regions of these fascinating compound particles can then be solidified to create thin shells.”
- Supercritical microfluidics: Opportunities in flow-through chemistry and materials science (2012, background): “In liquid low pressure microsystems, droplets, jets [53,54] (Fig.”