Mechanical thrombectomy after intravenous alteplase versus alteplase alone after stroke (THRACE): a randomised controlled trial.

By S. Bracard, X. Ducrocq, J. Mas, M. Soudant, C. Oppenheim, T. Moulin, F. Guillemin. Lancet Neurology, 2016

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Thrombectomy 6 to 24 Hours after Stroke with a Mismatch between Deficit and Infarct (2018, neutral): “Symptomatic intracranial hemorrhage at 24 hr† 6 (6) 3 (3) 3 (−3 to 8) 2 (1 to 7)”
The Evolution of the Modified Rankin Scale and Its Use in Future Stroke Trials (2017, methodology): “Such trials include PROACT II, TREVO 2 (Thrombectomy REvascularization of Large Vessel Occlusions), REVASCAT, THRACE, and ECASS III (European Cooperative Acute Stroke Study).(13,40,41,45,46) These trials illustrate that dichotomous approaches to the mRS can be statistically significant when ordinal ”
Multisociety Consensus Quality Improvement Revised Consensus Statement for Endovascular Therapy of Acute Ischemic Stroke (2018, neutral): “Similarly, the THERAPY (18) and Trial and Cost Effectiveness Evaluation of Intra-arterial Thrombectomy in Acute Ischemic Stroke (THRACE) (8) trials reported 38% and 53% rates of mRS score 0–2 at 90 days, respectively, and, in the perprotocol population of the Pragmatic Ischaemic Thrombectomy Evaluat”
Deep learning guided stroke management: a review of clinical applications (2017, result): “22 Contrary to the results of earlier studies, these recent trials consistently showed superior clinical outcomes, with use of neuroimaging criteria for patient selection being a key component of these trials.”