The use of zebrafish to understand immunity.

By N. Trede, D. Langenau, D. Traver, A. Look, Leonard I. Zon. Immunity, 2004

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Ontogeny of the immune system of fish. (2006, background): “In zebrafish, as described above, both morphological evidence [28] and expression of T-cell markers (lck, TcR a) [11,29] confirm the early occurrence of T lymphocytes in the fish thymus.”
Distinct signals from the microbiota promote different aspects of zebrafish gut differentiation. (2006, background): “Zebrafish are well suited for studying bacterial–host interactions: like mammals, they possess both adaptive and innate immune systems for modulating interactions with microbes (Trede et al., 2004), and their tissue transparency allows visualization of internal organs and fluorescent protein-express”