The Influence of the Gut Microbiome on Cancer, Immunity, and Cancer Immunotherapy.
By V. Gopalakrishnan, Beth A. Helmink, C. Spencer, A. Reuben, J. Wargo. Cancer Cell, 2018
1,163 citations recorded by the source corpus.
Subfields: Infectious Diseases, Molecular Biology, Oncology
View Paper: https://www.semanticscholar.org/paper/ef32f345e706cb0acf41fe704865c7dd29e8bef1
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In Infectious Diseases
In Molecular Biology
In Oncology
Citations in the corpus
- Interaction between microbiota and immunity in health and disease (2020, background): “microbiome in anticancer immune surveillance and immunotherapy may hold great promise in optimizing treatment responses in cancer patients, and has been reviewed elsewhere in greater detail.(13,196) Aside from the gut microbiome, most recent research begins to explore the role of intra-tumor tissue ”
- The Gut Microbiota and Inflammation: An Overview (2020, background): “There is strong evidence for gut microbial influence on tumour formation local to the gastro-intestinal tract and on response to cancer treatment [140].”
- The microbiome and human cancer (2021, background): “Although most proposed cancer-microbe relationships focus on gut microbiota (30, 32, 33), recent studies also contentiously suggest the existence, metabolic activity, and functional importance of intratumoral microbiota using a combination of imaging, sequencing, and cultivation techniques and genet”
- Hallmarks of Cancer: New Dimensions. (2022, background): “Beyond the causal links to colon cancer and melanoma, the gut microbiome’s demonstrable ability to elicit the expression of immunomodulatory chemokines and cytokines that enter the systemic circulation is evidently also capable of affecting cancer pathogenesis and response to therapy in other organs”
- A Review of Colorectal Cancer in Terms of Epidemiology, Risk Factors, Development, Symptoms and Diagnosis (2021, background): “Microbial manipulation in the clinical setting by administrating targeted design probiotics may reduce proinflammatory and anti-inflammatory cytokines and locally alter immunity that positively impacts cancer therapies results [152].”