Apoptosis versus oncotic necrosis in hepatic ischemia/reperfusion injury.

By H. Jaeschke, J. Lemasters. Gastroenterology, 2003

615 citations recorded by the source corpus.

Subfields: Molecular Biology, Surgery

View Paper: https://www.semanticscholar.org/paper/ef0b15e5f415ffdefda9553de32c5deeaad03c1a

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. A. Ramachandran
2. Mitchell R. McGill
3. Robert F. Schwabe
4. H. Jaeschke
5. D. Brenner

In Surgery

1. A. Ramachandran
2. Mitchell R. McGill
3. H. Jaeschke

Citations in the corpus

• OXIDANT STRESS, MITOCHONDRIA AND CELL DEATH MECHANISMS IN DRUG-INDUCED LIVER INJURY: LESSONS LEARNED FROM ACETAMINOPHEN HEPATOTOXICITY (2012, methodology): “Although both apoptosis and APAP-induced necrosis cause DNA fragmentation, there is a clear distinction in the staining patterns with the terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling (TUNEL) assay between the two forms of cell death (Jaeschke and Lemasters, 2003), which is”
• Mechanisms of Liver Injury. I. TNF-α-induced liver injury: role of IKK, JNK, and ROS pathways (2006, background): “Hepatocytes often show morphological features of apoptosis and necrosis, for which the term “necrapoptosis” has been coined (16).”
• The mechanism underlying acetaminophen-induced hepatotoxicity in humans and mice involves mitochondrial damage and nuclear DNA fragmentation. (2012, positive): “age, chromatin condensation, and formation of apoptotic bodies as well as extensive caspase activation (60).”