Aperiodic EEG and 7T MRSI evidence for maturation of E/I balance supporting the development of working memory through adolescence
By Shane D. McKeon, Maria I. Perica, A. Parr, Finnegan J. Calabro, William Foran, Hoby Hetherington, Chan-Hong Moon, Beatriz Luna. 2023
Subfields: Cognitive Neuroscience, Developmental Neuroscience
Citations in the corpus
- Age and gender-related neurophysiological changes in sleep and wake states during childhood (2026, unknown): “A substantial body of literature indicates that the slope of the aperiodic component during wakefulness decreases with brain maturation (Cellier et al., 2021; McKeon et al., 2024), suggesting that excitatory activity in wakefulness increases as one gets older.”
- Reevaluating the neural noise in dyslexia using biomarkers from electroencephalography and high-resolution magnetic resonance spectroscopy (2025, unknown): “Following a recent study examining developmental changes in both EEG and MRS E/I biomarkers ( McKeon et al., 2024 ), we calculated an additional measure of Glu/GABA+ imbalance, computed as the absolute residual value from the linear regression of Glu predicted by GABA+ with greater values…”
- Heterochronous laminar maturation in the human prefrontal cortex (2025, unknown): “By combining myelin-sensitive MRI with measures of EEG aperiodic activity, we uncovered that higher R1 was related to a functional index of higher E/I balance 59,60 and a faster timescale of neural activity 61,62 .”
- Exploring Background Aperiodic Electroencephalography (EEG) Activity in the Bucharest Early Intervention Project (2024, unknown): “Based on previous studies that have connected aperiodic activity to working memory task performance (McKeon et al., 2023), this change could indicate the maturation of cognitive control mechanisms in adolescence.”