Risks of untreated and treated isolated systolic hypertension in the elderly: meta-analysis of outcome trials.

By J. Staessen, Jerzy Gąsowski, J. G. Wang, L. Thijs, E. Hond, J. Boissel, J. Coope, T. Ekbom, F. Gueyffier, Li-sheng Liu and 3 more. The Lancet, 2000

1,215 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine, Nutrition and Dietetics

View Paper: https://www.semanticscholar.org/paper/ee852d8d5b73fc430abe36c188214c74227dda2b

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cardiology and Cardiovascular Medicine

1. S. Laurent
2. John P. A. Ioannidis
3. H. S. Boudier
4. B. K. Pedersen
5. B. Saltin

Citations in the corpus

• Contradicted and initially stronger effects in highly cited clinical research. (2005, result): “The findings of 20 highly cited articles (44%) were replicated (also with a larger sample size in subsequent research compared with the original highly cited study) and 11 (24%) had remained largely unchallenged.(58-78)”
• 2007 ESH‐ESC Guidelines for the management of arterial hypertension (2007, background): “(10,23,292,471) Evidence for the benefit of treating grade 1 hypertensives is admittedly more scant, as specific trials have not addressed the issue.”