WRKY Transcription Factors: Molecular Regulation and Stress Responses in Plants

By Ujjal J Phukan, G. Jeena, R. Shukla. Frontiers in Plant Science, 2016

617 citations recorded by the source corpus.

Plants in their natural habitat have to face multiple stresses simultaneously. Evolutionary adaptation of developmental, physiological, and biochemical parameters give advantage over a single window of stress but not multiple. On the other hand transcription factors like WRKY can regulate diverse responses through a complicated network of genes. So molecular orchestration of WRKYs in plant may provide the most anticipated outcome of simultaneous multiple responses. Activation or repression through W-box and W-box like sequences is regulated at transcriptional, translational, and domain level. Because of the tight regulation involved in specific recognition and binding of WRKYs to downstream promoters, they have become promising candidate for crop improvement. Epigenetic, retrograde and proteasome mediated regulation enable WRKYs to attain the dynamic cellular homeostatic reprograming. Overexpression of several WRKYs face the paradox of having several beneficial affects but with some unwanted traits. These overexpression-associated undesirable phenotypes need to be identified and removed for proper growth, development and yeild. Taken together, we have highlighted the diverse regulation and multiple stress response of WRKYs in plants along with the future prospects in this field of research.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/ee3ab77572495bef78e059233bb9e00bcff40be6

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. A. Howling
2. Vincent Chiang
3. S. Asaf
4. A. Waskow
5. A. Raza
6. I. Furno
7. M. Numan

In Plant Science

1. Xujun Chen
2. A. Howling
3. C. Li
4. Han Wang
5. Vincent Chiang
6. Zejian Guo
7. S. Asaf
8. A. Waskow

Citations in the corpus

• Plant Secondary Metabolite Biosynthesis and Transcriptional Regulation in Response to Biotic and Abiotic Stress Conditions (2021, background): “Plant WRKY TFs are largely involved in stress responses; they can be regulated by wound or jasmonic acid signaling, and they alter the expression of genes involved in the biosynthesis of various SMs such as alkaloids, terpenoids, and their subclasses [221].”
• Cooperative Regulation of Flavonoid and Lignin Biosynthesis in Plants (2021, background): “…contain the so-called AC elements, including AC-I (ACCTACC), AC-II (ACCAACC), and AC-III (ACCTAAC), which are recognized by transcription factors (Raes et al., 2003), some of R2R3-MYB transcription factors directly bind to AC cis-elements in monolignol biosynthetic gene promoters to regulate…”
• Mechanisms of Plasma-Seed Treatments as a Potential Seed Processing Technology (2021, background): “Moreover, there are also interactions between MAPK cascades and this WRKY family and they can also activate PR proteins [183].”
• Impact of Climate Change on Crops Adaptation and Strategies to Tackle Its Outcome: A Review (2019, background): “Another important family of TFs are WRKY which are extensively distributed in relation to abiotic [209] and biotic stresses in plants [210].”
• WRKY transcription factors: evolution, binding, and action (2019, positive): “Since the first report of the WRKY gene from sweet potato (Ishiguro and Nakamura 1994), numerous WRKY genes from a wide range of plant species have been characterized and shown to participate in growth, development, metabolism, and responses to environmental cues (Chi et al. 2013; Schluttenhofer and”