Exchange-coupled magnetic nanoparticles for efficient heat induction.
By Jae‐Hyun Lee, Jung-tak Jang, Jin-sil Choi, S. Moon, S. Noh, Ji-wook Kim, Jin-Gyu Kim, Il-Sun Kim, K. Park, J. Cheon. Nature Nanotechnology, 2011
1,252 citations recorded by the source corpus.
The conversion of electromagnetic energy into heat by nanoparticles has the potential to be a powerful, non-invasive technique for biotechnology applications such as drug release, disease treatment and remote control of single cell functions, but poor conversion efficiencies have hindered practical applications so far. In this Letter, we demonstrate a significant increase in the efficiency of magnetic thermal induction by nanoparticles. We take advantage of the exchange coupling between a magnetically hard core and magnetically soft shell to tune the magnetic properties of the nanoparticle and maximize the specific loss power, which is a gauge of the conversion efficiency. The optimized core-shell magnetic nanoparticles have specific loss power values that are an order of magnitude larger than conventional iron-oxide nanoparticles. We also perform an antitumour study in mice, and find that the therapeutic efficacy of these nanoparticles is superior to that of a common anticancer drug.
Subfields: Biomaterials, Biomedical Engineering, Statistical and Nonlinear Physics
View Paper: https://www.semanticscholar.org/paper/ee11d41bf0d1715df3a84cc649ab2bdce3c9496e
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
- D. Litvinov
- A. Kolhatkar
- A. C. Jamison
- Richard C. Willson
- T. R. Lee
- Hansoo Park
- Jee-Hyun Yoon
- Jeremy B. Vines
Citations in the corpus
- Gold Nanoparticles for Photothermal Cancer Therapy (2019, background): “, 2011), doped iron oxide (Lee et al., 2011; Fantechi et al., 2014; Gordon et al., 2014) and super-paramagnetic iron oxide nanoparticles (SPION) (Le Renard et al.”
- Tuning the Magnetic Properties of Nanoparticles (2013, background): “[125] demonstrated that their composite particles exhibited a significant enhancement in SLP (1000 to 4000 W/g) as compared to single-component MNPs (100 to 450 W/g) and commercial Ferridex nanoparticles (115 W/g).”