A genome-wide view of the spectrum of spontaneous mutations in yeast

By Michael Lynch, Way Sung, K. Morris, N. Coffey, Christian R. Landry, Erik B. Dopman, W. J. Dickinson, Kazufusa Okamoto, Shilpa Kulkarni, Daniel L. Hartl and 1 more. Proceedings of the National Academy of Sciences of the United States of America, 2008

722 citations recorded by the source corpus.

Subfields: Genetics, Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/ed9d883476f8edb9f617cdbb7a616181c01e7cd8

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Genetics

1. Heewook Lee
2. Patricia L. Foster
3. Ellen Popodi
4. Haixu Tang

In Molecular Biology

1. J. Dalton‐Morgan
2. P. Sharp
3. Haixu Tang
4. Chongmei Dong
5. Kate Vincent

In Plant Science

1. J. Dalton‐Morgan
2. P. Sharp
3. Chongmei Dong
4. Kate Vincent

Citations in the corpus

• Rate, molecular spectrum, and consequences of human mutation (2010, neutral): “33 × 10) (13) and Escherichia coli (approximately 0.”
• Spontaneous Mutation Accumulation Studies in Evolutionary Genetics (2009, neutral): “If a is not constant, implying that Var(a) is positive, using these estimators will give lower and upper bound estimates of U and E(a), respectively (Lynch & Walsh 1998).”
• A Modified TILLING Method for Wheat Breeding (2009, background): “33 × 10–9 per site per cell division and estimated a rate of 10–10 in humans (Lynch et al., 2008).”
• Rate and molecular spectrum of spontaneous mutations in the bacterium Escherichia coli as determined by whole-genome sequencing (2012, background): “Recent results from applying this protocol to microbes include the genomewide spontaneous mutational spectrum in Saccharomyces cerevisiae (10) and the mutational consequences of loss of DNA oxidative damage repair in Salmonella typhimurium (11).”