Cognitive deficits in unaffected first-degree relatives of schizophrenia patients: a meta-analytic review of putative endophenotypes.

By Beth E Snitz, A. MacDonald, Cameron S. Carter. Schizophrenia bulletin, 2005

742 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Genetics, Psychiatry and Mental health

View Paper: https://www.semanticscholar.org/paper/ed3a4eec0ff949e408cd3d7b727797a24f36bf62

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cognitive Neuroscience

1. Murat Yücel
2. R. Keefe
3. J. van Os
4. Matcheri S. Keshavan
5. R. McCutcheon
6. Philip K. McGuire
7. E. Bora
8. Oliver D. Howes

In Genetics

1. J. van Os
2. Matcheri S. Keshavan
3. R. Tandon
4. H. Nasrallah

In Psychiatry and Mental health

1. R. McCutcheon
2. J. van Os
3. Murat Yücel
4. R. Keefe
5. Matcheri S. Keshavan
6. E. Bora
7. Oliver D. Howes
8. R. Tandon

Citations in the corpus

• Cognitive functioning in prodromal psychosis: a meta-analysis. (2012, result): “Moreover, meta-analyses of genetic highrisk samples revealed neurocognitive deficits in unaffected adolescents(64) and adult first-degree relatives, with similar effect sizes.(65) Our results indicate that vulnerability to psychosis is associated with significant cognitive impairment.”
• Schizophrenia, "just the facts" 4. Clinical features and conceptualization. (2009, positive): “…“just the fa 2005; Trandafir et al., 2006; Whalley et al., 2007) and is likely related to a patient's genetic susceptibility to schizophrenia (Snitz et al., 2006; Fusar-Poli et al., 2007; Touloupolou et al., 2007); (ix) cognitive impairment is a strong predictor of poor social and…”
• Cognitive endophenotypes of bipolar disorder: a meta-analysis of neuropsychological deficits in euthymic patients and their first-degree relatives. (2009, background): “In this context, while there is convincing evidence regarding the value of cognitive deficits as putative endophenotypes of schizophrenia (Gur et al., 2007; Pantelis et al., in press; Snitz et al., 2006), the value of such markers as endophenotypes of bipolar disorder (BD) is a largely understudied ”
• Meta-analyses of cognitive functioning in euthymic bipolar patients and their first-degree relatives (2007, background): “2004; Szoke et al. 2005 ; Snitz et al. 2006) describe the largest effect sizes (d=0.5 to 0.6) for executive functioning and verbal memory, with somewhat different effect sizes for different executive tests used and greater effect sizes in multiplex families (Heydebrand, 2006).”
• Cognitive impairment in schizophrenia: aetiology, pathophysiology, and treatment (2023, background): “The relatives of people with schizophrenia also show cognitive deficits [85, 86], and twin studies suggest that a significant proportion of the variance in cognition and schizophrenia risk is due to shared Fig.”