Fatigue and basal ganglia.

By A. Chaudhuri, P. Behan. Journal of Neurological Sciences, 2000

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Fatigue and fatigability in neurologic illnesses (2013, background): “Other brain areas, including frontal lobes and basal ganglia, are also likely important in regulating behavior relative to homeostatic factors and other cues.(43) One current hypothesis suggests that these CNS structures act as a “central governor” to limit energy utilization and avoid potential ene”
Mental fatigue: costs and benefits. (2008, background): “Chaudhuri and Behan (2000) propose that fatigue is a symptom of diseases that affect the basal ganglia, disrupting the integration of perceived reward value in the initiation of voluntary activities (Nauta, 1986).”
Mental fatigue, motivation and action monitoring. (2006, background): “Indeed, Chaudhuri and Behan (2000) proposed that the symptoms of mental fatigue reported by their neurological patients may be due to a failure of the DA mediated functions of the BG.”