Targeted random mutagenesis: the use of ambiguously synthesized oligonucleotides to mutagenize sequences immediately 5' of an ATG initiation codon.

By M. Matteucci, H. Heyneker. 1983

Citations in the corpus

• Quantitative missense variant effect prediction using large-scale mutagenesis data (2017, neutral): “Variant coverage depended on experimental details such as the protocol used for library generation (e.g., doped oligomer [Matteucci and Heyneker, 1983] versus site saturation mutagenesis [Jain and Varadarajan, 2014]), the number of clones generated, and the sequencing depth.”