The biology of cell locomotion within three-dimensional extracellular matrix

By Peter Friedl, E. Bröcker. Cellular and Molecular Life Sciences (CMLS), 2000

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Tumour-cell invasion and migration: diversity and escape mechanisms (2003, background): “Pro-collagenase-1 (matrix metalloproteinase-1) binds the alpha(2)beta(1) integrin upon release from keratinocytes migrating on type I collagen.”
Balancing forces: architectural control of mechanotransduction (2011, neutral): “For instance, cells cultured in 1D, 2D and 3D show pronounced differences in their motilit”
From Cell–ECM interactions to tissue engineering (2004, background): “Adhesive glycoproteins are a class of ECM molecules including interactive glycoproteins that exsist in several variant forms and possess multiple binding domains capable of binding collagen and proteoglycans, as well as binding to the cell surface (Friedl and Brocker, 2000).”
Compensation mechanism in tumor cell migration (2003, background): “To understand how proteases contribute to cell migration, the concept of pericellular proteolysis has to be integrated into the current paradigm on cell migration as a supramolecular process (Lauffenburger and Horwitz, 1996; Friedl and Brocker, 2000 ).”