A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis.

By A. Brack, I. Conboy, M. Conboy, Jeanne Shen, T. Rando. Cell Stem Cell, 2008

662 citations recorded by the source corpus.

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

Satellite cells and the muscle stem cell niche. (2013, background): “Second, the activation of Wnt signaling in differentiating myoblasts antagonizes Notch signaling and facilitates terminal differentiation (65).”
Building muscle: molecular regulation of myogenesis. (2012, background): “A transition from Notch signaling, which functions to expand the progenitor pool of adult skeletal muscle upon injury, toward canonical Wnt3a signaling has been reported to be required for efficient myoblast differentiation and muscle regeneration (Brack et al. 2008).”
Satellite Cells and Skeletal Muscle Regeneration (2015, positive): “A switch from Notch to the canonical Wnt signaling pathway has been shown to be critical for the transition to myoblast differentiation (39).”