The Angular Gyrus
By Mohamed L. Seghier. The Neuroscientist, 2013
862 citations recorded by the source corpus.
There is considerable interest in the structural and functional properties of the angular gyrus (AG). Located in the posterior part of the inferior parietal lobule, the AG has been shown in numerous meta-analysis reviews to be consistently activated in a variety of tasks. This review discusses the involvement of the AG in semantic processing, word reading and comprehension, number processing, default mode network, memory retrieval, attention and spatial cognition, reasoning, and social cognition. This large functional neuroimaging literature depicts a major role for the AG in processing concepts rather than percepts when interfacing perception-to-recognition-to-action. More specifically, the AG emerges as a cross-modal hub where converging multisensory information is combined and integrated to comprehend and give sense to events, manipulate mental representations, solve familiar problems, and reorient attention to relevant information. In addition, this review discusses recent findings that point to the existence of multiple subdivisions in the AG. This spatial parcellation can serve as a framework for reporting AG activations with greater definition. This review also acknowledges that the role of the AG cannot comprehensibly be identified in isolation but needs to be understood in parallel with the influence from other regions. Several interesting questions that warrant further investigations are finally emphasized.
View Paper: https://www.semanticscholar.org/paper/eb082a58ab7674ca768aaa6e3d459d21afb98f79
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
- Xavier Guell
- John D. E. Gabrieli
- Marie Amalric
- Jeremy D. Schmahmann
- Denise Dörfel
- Jan-Peter Lamke
- Henrik Walter
- Susanne Erk
Citations in the corpus
- Common and differential neural networks of emotion regulation by Detachment, Reinterpretation, Distraction, and Expressive Suppression: A comparative fMRI investigation (2014, background): “Seghier (2013) points to the angular gyrus serving as a cross-modal hub where converging multisensory information is combined and integrated to comprehend and give sense to events, manipulate mental representations, and reorient attention to relevant information.”
- TRIPLE REPRESENTATION OF LANGUAGE, WORKING MEMORY, SOCIAL AND EMOTION PROCESSING IN THE CEREBELLUM: CONVERGENT EVIDENCE FROM TASK AND SEED-BASED RESTING-STATE FMRI ANALYSES IN A SINGLE LARGE COHORT (2018, result): “This notwithstanding, seed locations are consistent with previous reports in the literature of brain function: working memory (e.g. Koenigs et al., 2009), language (e.g. Seghier, 2013), emotion processing (e.g. Dapretto et al., 2006), social processing (e.g. Bigler et al., 2007).”
- Origins of the brain networks for advanced mathematics in expert mathematicians (2016, background): “deactivated by meaningless compared with meaningful general-knowledge statements in both groups, as previously reported (32, 35).”