Structural Biology and Crystallization Communications Dufs: Families in Search of Function

By Alex Bateman, P. Coggill, Robert D. Finn

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. Sean R. Eddy
2. Robert D. Finn
3. Jaina Mistry
4. Alex Bateman
5. Liisa Holm
6. Johannes Söding
7. Simon C. Potter
8. Jody Clements

Citations in the corpus

• The Pfam protein families database in 2019 (2018, background): “Despite our continual efforts to rename DUFs based on functional information found in both the scientific literature and other protein family databases (22), the fraction of Pfam entries with no known function has increased over the past decade.”
• The Pfam protein families database (2011, methodology): “As previously reported (16), DUFs are, on an average, less widely distributed on the evolutionary tree than functionally annotated families.”