Functional neuroimaging correlates of mental fatigue induced by cognition among chronic fatigue syndrome patients and controls

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Mental fatigue impairs physical performance in humans. (2009, background): “This area of the prefrontal cortex is affected by mental fatigue (14, 39) and provides a neurobiological rationale for impaired performance in a subsequent physical task.”
Myalgic encephalomyelitis: International Consensus Criteria (2011, background): “Patients’ perception that simple mental tasks require substantial effort is supported by brain scan studies that indicate greater source activity and more regions of the brain are utilized when processing auditory and spatial cognitive information [78-80].”
Muscle fatigue: what, why and how it influences muscle function (2008, unknown): “(Cook et al. 2007).”