Potent derivatives of glucagon-like peptide-1 with pharmacokinetic properties suitable for once daily administration.

By L. Knudsen, P. F. Nielsen, P. O. Huusfeldt, N. L. Johansen, K. Madsen, Freddy Zimmerdahl Pedersen, H. Thøgersen, M. Wilken, H. Agersø. Journal of Medicinal Chemistry, 2000

715 citations recorded by the source corpus.

Subfields: Endocrinology, Diabetes and Metabolism, Molecular Biology, Pharmacology

View Paper: https://www.semanticscholar.org/paper/e9a861e782e1b4b112b3a302b5d3f52bc426f0d5

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In Endocrinology, Diabetes and Metabolism

1. Josephine M. Egan
2. Wook Kim
3. M. Nauck

In Molecular Biology

1. M. Nauck
2. Josephine M. Egan
3. Wook Kim

Citations in the corpus

• The Role of Incretins in Glucose Homeostasis and Diabetes Treatment (2008, background): “After subcutaneous injection, maximum plasma concentration is reached after 10 to 14 h, and it has a half-life of 11 to 13 h (Knudsen et al., 2000; Agersø et al., 2002).”
• Efficacy and Safety Comparison of Liraglutide, Glimepiride, and Placebo, All in Combination With Metformin, in Type 2 Diabetes (2008, background): “Adverse events 11 (5) 23 (10) 29 (12) 8 (3) 2 (2)”
• Protein drug stability: a formulation challenge (2005, neutral): “fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=2641">GLP1 ) (Ref”