Investigating the prevalence of complex fiber configurations in white matter tissue with diffusion magnetic resonance imaging

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Anatomically-constrained tractography: Improved diffusion MRI streamlines tractography through effective use of anatomical information (2012, background): “Previous research suggested that at typical DWimaging resolutions, around one-third of white matter voxels in the brain contain such complex architecture (Behrens et al., 2007); however,more recent evidence indicates that this figuremay be as high as 90% (Jeurissen et al., 2012).”
Multi-tissue constrained spherical deconvolution for improved analysis of multi-shell diffusion MRI data (2014, neutral): “It also complicates the interpretation of DTI metrics, which are often suggested for use as surrogate markers of WM ‘integrity’ (Jones, 2010; Vos et al., 2012; Wheeler-Kingshott and Cercignani, 2009; Jeurissen et al., 2013).”
Denoising of diffusion MRI using random matrix theory (2016, methodology): “Second, the fiber orientations are selected as the distinct peaks of the fODF with an amplitude exceeding a user-defined threshold (Jeurissen et al., 2013).”