The S100A8–serum amyloid A3–TLR4 paracrine cascade establishes a pre-metastatic phase

By Sachie Hiratsuka, A. Watanabe, Y. Sakurai, Sachiko Akashi-Takamura, S. Ishibashi, K. Miyake, M. Shibuya, Shizuo Akira, H. Aburatani, Y. Maru. Nature Cell Biology, 2008

670 citations recorded by the source corpus.

Subfields: Immunology, Molecular Biology, Pulmonary and Respiratory Medicine

View Paper: https://www.semanticscholar.org/paper/e95f07365e79d4374310334cbf2246e31fdab384

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Immunology

1. V. Plaks
2. Larry Norton
3. Swarnali Acharyya
4. J. Massagué
5. Thordur Oskarsson
6. Zena Werb
7. Pengfei Lu

In Molecular Biology

1. V. Plaks
2. Zena Werb
3. K. Kessenbrock
4. Larry Norton
5. Thordur Oskarsson
6. J. Massagué
7. Xuetao Cao
8. Yang Liu

In Pulmonary and Respiratory Medicine

1. J. Massagué
2. E. Hay

Citations in the corpus

• Characteristics and Significance of the Pre-metastatic Niche. (2016, background): “These Mac1+ myeloid cells enhance pre-metastatic niche formation in an inflammatory state, thus promoting the migration of primary tumor cells to the secondary lung sites (Hiratsuka et al., 2008).”
• Matrix Metalloproteinases: Regulators of the Tumor Microenvironment (2010, background): “It appears that SAA3 triggers toll-like receptor 4 (TLR4) signaling in lung-infiltrating myeloid cells leading to activation of the nuclear factor κB (NF-κB) pathway (Hiratsuka et al., 2008).”