The Population Dynamics and Control of Tuberculosis

By C. Dye, B. Williams. Science, 2010

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The challenge of new drug discovery for tuberculosis (2011, background): “We studied 14 different physicochemical features, including molecular weight, lipophilicity and polar surface area of first- and second-line TB drugs, and compared these properties to known marketed non-antibacterial compounds (1,663) identified from the Prous Integrity database (http://integrity.”
The Hologenome Concept: Human, Animal and Plant Microbiota (2014, background): “However, when the host immune system suffers, as a result of aging, malnutrition, diabetes, tobacco use, alcohol abuse, or HIV/AIDS infection, the bacterium converts into an active pathogen (Dye and Williams 2010).”
Mycobacterium tuberculosis: Success through dormancy (2012, background): “Currently, up to 9 million new cases of TB arise each year, more than ever before (Dye & Williams, 2010).”
Risk Factors for Tuberculosis (2013, background): “Rapid urbanization [105, 106] witnessed in developing countries and socioeconomic status (SES) of individuals has also been shown to have influence on a person’s susceptibility to infection.”
HIV and Tuberculosis: a Deadly Human Syndemic (2011, background): “The transmission of TB is a product of the infectiousness of the index case and the duration of infectiousness (80), both of which can be affected by HIV.”