Microvesicles released from human renal cancer stem cells stimulate angiogenesis and formation of lung premetastatic niche.
By Cristina Grange, Marta Tapparo, F. Collino, L. Vitillo, C. Damasco, M. Deregibus, C. Tetta, B. Bussolati, G. Camussi. Cancer Research, 2011
845 citations recorded by the source corpus.
Subfields: Cancer Research, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/e907ec696e64b000e82e12c8c45983c5f8a44576
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In Cancer Research
In Molecular Biology
- Raghu Kalluri
- Asfar S. Azmi
- Fazlul H. Sarkar
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- David W. Greening
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Citations in the corpus
- Exosomes in Tumor Microenvironment Influence Cancer Progression and Metastasis (2013, background): “Moreover, this study revealed that CD105-positive exosomes contribute in establishing a pre-metastatic niche in the lung microenvironment of SCID mice by upregulating MMP2, MMP9, and VEGFR1 [41].”
- Targeting cancer stem cell pathways for cancer therapy (2020, background): “[424] [425] [426] This CSC plasticity has also been demonstrated in other tumors, including neuroblastoma, renal, breast, and ovarian cancer.”
- Exosomes in cancer development, metastasis, and immunity (2019, background): “In addition, microvesicles released by CD105+ renal cell carcinoma stem cells triggered angiogenesis and promoted the formation of a pre-metastatic niche in the lung [101].”
- SORTING IT OUT: REGULATION OF EXOSOME LOADING (2014, background): “Exosome-mediated signaling in tumors is thus affected by a variety of stress conditions [111], and promotes tumor progression through communication between the tumor and surrounding stromal tissue, activation of proliferative and angiogenic pathways, promotion of immune suppression, and initiation o”
- Exosomes and their roles in immune regulation and cancer. (2015, background): “[125] Grange C, Tapparo M, Collino F, Vitillo L, Damasco C, Deregibus MC, et al.”
- Review of the Isolation, Characterization, Biological Function, and Multifarious Therapeutic Approaches of Exosomes (2019, background): “CD105-positive MVs released from human renal cancer stem cells promote angiogenesis [131].”
- Exosomes in Cancer Development, Metastasis and Drug Resistance: A Comprehensive Review (2013, positive): “For example, Grange and colleagues showed that exosomes released from renal cells can promote angiogenesis in lung cancer ascites [153].”