Maturation time of new granule cells in the dentate gyrus of adult macaque monkeys exceeds six months

By Shawn Kohler, N. I. Williams, G. B. Stanton, J. Cameron, W. Greenough. 2011

184 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience

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In Cellular and Molecular Neuroscience

In Developmental Neuroscience

Citations in the corpus

Human Hippocampal Neurogenesis Persists throughout Aging (2018, neutral): “We only counted cells expressing specific markers at one time point, the time of demise, and expression of those markers may last a few weeks or months according to studies in primates (Kohler et al., 2011).”
Dynamics of hippocampal neurogenesis in adult humans (2013, positive): “Along with the extended period of immature features of the adult-born neurons in nonhuman primates (Kohler et al., 2011), and potentially humans, the relative proportion of adult-born neurons with unique functions in the human hippocampus may not be smaller than that in a middle-aged mouse.”
In contrast to many other mammals, cetaceans have relatively small hippocampi that appear to lack adult neurogenesis (2013, background): “The presence of DCX also reflects cumulative adult hippocampal neurogenesis over a period of 2 weeks to 6 months, although this period is species specific (Rao and Shetty 2004; Kohler et al. 2011).”
Neurogenesis in the striatum of the adult human brain. (2014, unknown): “The presence of the mature neuronal marker NeuN in many DCX-positive neurons does not necessarily imply that they are not newborn; in nonhuman primates, adult-born neurons in the dentate gyrus maintain DCX for at least 6 months and coexpress NeuN (Kohler et al., 2011), suggesting that they may retai”
Benzodiazepines And The Potential Trophic Effect Of Antidepressants On Dentate Gyrus Cells In Mood Disorders (2014, unknown): “Adult neurogenesis, like developmental neurogenesis, in non-human primates is about five times less than in mice (Kohler et al., 2011).”
Human adult neurogenesis: evidence and remaining questions (2018, background): “neurons might take several months in primates (Kohler et al., 2011), resulting in a heterogeneity of the granule cell population with a relatively large subpopulation of early neurons in waiting”