Metastasis: recent discoveries and novel treatment strategies.

By S. Eccles, D. Welch. The Lancet, 2007

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MicroRNAs — the micro steering wheel of tumour metastases (2009, background): “However, the molecular pathways underlying each step are still obscur”
Apoptosis, autophagy, necroptosis, and cancer metastasis (2015, background): “Furthermore, tumor cells must survive in the environment of reactive oxygen species (ROS) produced by endothelial cells when crossing the vessel or tissue barrier during the extravasation step [15,16].”
Detection, clinical relevance and specific biological properties of disseminating tumour cells (2008, background): “Most deaths from this class of tumours are caused by haematogenous spread of cancer cells into distant organs and their subsequent growth to overt metastase”