Central tolerance: learning self-control in the thymus

By K. Hogquist, T. Baldwin, S. Jameson. Nature reviews. Immunology, 2005

719 citations recorded by the source corpus.

Subfields: Endocrinology, Diabetes and Metabolism, Immunology

View Paper: https://www.semanticscholar.org/paper/e8dd7215432c007f360bf556440da68209e29dfa

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Endocrinology, Diabetes and Metabolism

1. P. Greenberg
2. A. Schietinger

In Immunology

1. A. Schietinger
2. P. Greenberg
3. S. Shalapour
4. M. Karin

Citations in the corpus

• Tolerance and Exhaustion: Defining Mechanisms of T cell Dysfunction (2013, positive): “Central tolerance is established during T cell development in the thymus, with thymocytes expressing T cell receptors (TCR) of too high affinity for self-antigen/MHC complexes eliminated (negative selection) [10].”