The Reference Genome Sequence of Saccharomyces cerevisiae: Then and Now

By S. Engel, F. Dietrich, D. Fisk, G. Binkley, R. Balakrishnan, M. Costanzo, S. Dwight, B. Hitz, K. Karra, R. Nash and 7 more. G3: Genes, Genomes, Genetics, 2013

408 citations recorded by the source corpus.

The genome of the budding yeast Saccharomyces cerevisiae was the first completely sequenced from a eukaryote. It was released in 1996 as the work of a worldwide effort of hundreds of researchers. In the time since, the yeast genome has been intensively studied by geneticists, molecular biologists, and computational scientists all over the world. Maintenance and annotation of the genome sequence have long been provided by the Saccharomyces Genome Database, one of the original model organism databases. To deepen our understanding of the eukaryotic genome, the S. cerevisiae strain S288C reference genome sequence was updated recently in its first major update since 1996. The new version, called “S288C 2010,” was determined from a single yeast colony using modern sequencing technologies and serves as the anchor for further innovations in yeast genomic science.

Subfields: Food Science, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/e878f3bd94426fd9b7fbca7fe83553f0b8024ce1

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. Tobin R. Sosnick
2. Joshua A. Riback

Citations in the corpus

• Stress-triggered phase separation is an adaptive, evolutionarily tuned response (2017, methodology): “The yeast proteome (translated coding sequences) was retrieved from the Saccharomyces Genome Database (SGD) (Engel et al., 2014), release 64-2-1.”