Substituting an alpha-helix switches the sequence-specific DNA interactions of a repressor.

By R. Wharton, E. Brown, M. Ptashne. 1984

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1. Travis N. Mavrich
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Citations in the corpus

• Evolution of Superinfection Immunity in Cluster A Mycobacteriophages (2019, background): “Although repressor DNA-binding recognition can be mutationally altered with a small number of amino acid substitutions (18, 19), immune specificity itself involves multiple regulatory elements, including secondary immunity loci, multiple operators, and additional phage-encoded proteins, and thus, sw”