The cytokine storm in COVID-19: An overview of the involvement of the chemokine/chemokine-receptor system

By F. Coperchini, Luca Chiovato, L. Croce, F. Magri, M. Rotondi. Cytokine & growth factor reviews, 2020

1,206 citations recorded by the source corpus.

Highlights • COVID-19 pandemic is raging worldwide and is putting health-care systems under severe strain.• The “cytokine storm” and the subsequent ARDS result from the effects of the combination of several immune-active molecules.• The “cytokine storm” is the most dangerous and potentially life-threatening event related to COVID-19.• The chemokine system is involved in the pathogenesis of severe clinical sequelae of COVID-19, similarly to SARS and MERS.

Subfields: Infectious Diseases, Neurology

View Paper: https://www.semanticscholar.org/paper/e7d11780a6ed07f0efe6c54127c7e3ba8b73fbbf