Kinesin Walks Hand-Over-Hand
By Ahmet Yildiz, M. Tomishige, R. Vale, P. Selvin. Science, 2004
940 citations recorded by the source corpus.
Subfields: Cell Biology, Condensed Matter Physics
View Paper: https://www.semanticscholar.org/paper/e7bd6c4ff405dae686795ef7a3f85cb4cfc76684
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In Cell Biology
In Condensed Matter Physics
Citations in the corpus
- Ultra-high resolution imaging by fluorescence photoactivation localization microscopy. (2006, background): “Demonstrated precisions in the range of 2 nm have been realized (52,53).”
- How do site-specific DNA-binding proteins find their targets? (2004, background): “Nevertheless, such resolutions are realizable: recent experiments on the translocation of myosin and kinesin motor proteins along actin and tubulin ®laments, respectively, have achieved spatial resolutions in the nanometer range and time resolutions close to 1 ms (76,77).”
- Learning rates and states from biophysical time series: a Bayesian approach to model selection and single-molecule FRET data. (2009, neutral): “, the folding/unfolding rates of a ribozyme) via statistical inference (1, 2, 3, 4, 5, 6, 7, 8, 9).”
- Molecular motor traffic: From biological nanomachines to macroscopic transport (2006, methodology): “After a kinesin has bound to the microtubule, it walks along a single protofilament without sidesteps [53] in a ‘hand-over-hand’ manner [4,6] as schematically shown in Fig.”
- Kinesin motor mechanics: binding, stepping, tracking, gating, and limping. (2007, background): “(38,19), attaching the fluorophore dye to a position close to the common stalk can also introduce an offset leading to alternation in the apparent step size: this is a similar geometric phenomenon.”
- 'Life is motion': multiscale motility of molecular motors (2005, background): “There is now some direct experimental evidence that both two-headed myosin V on actin filaments [23] and two-headed kinesin on microtubules [24–26] step forward in such a ‘hand-over-hand’ manner.”
- Single-molecule analysis of dynein processivity and stepping behavior. (2006, background): “…could be fit to a single exponential (consistent with a single ATP binding event driving a step), whereas the dwell-time distribution for head movements were best fit by a convolution of two exponentials (consistent with two ATP binding events driving a step) (Yildiz et al., 2003, 2004).”