Epidemiology and Management of Hepatocellular Carcinoma

By J. D. Yang, Lewis R. Roberts. Infectious Disease Clinics of North America, 2010

623 citations recorded by the source corpus.

Hepatocellular carcinoma (HCC) is a major world health problem because of the high incidence and case fatality rate. In most patients, the diagnosis of HCC is made at an advanced stage, which limits the application of curative treatments. Most HCCs develop in patients with underlying chronic liver disease. Chronic viral hepatitis B and C are the major causes of liver cirrhosis and HCC. Recent improvements in treatment of viral hepatitis and in methods for surveillance and therapy for HCC have contributed to better survival of patients with HCC. This article reviews the epidemiology, cause, prevention, clinical manifestations, surveillance, diagnosis, and treatment approach for HCC.

Subfields: Epidemiology, Hepatology

View Paper: https://www.semanticscholar.org/paper/e781f5102d2811cf968297e54609feff957b877f

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. M. Kudo
2. M. Sherman
3. Lewis R. Roberts
4. Jordi Bruix1 , 2

In Hepatology

1. Lewis R. Roberts
2. M. Kudo
3. M. Colombo
4. M. Sherman
5. Jordi Bruix1 , 2
6. J. Llovet

Citations in the corpus

• Global patterns of hepatocellular carcinoma management from diagnosis to death: the BRIDGE Study (2015, result): “The high prevalence of male patients in this study support previous findings that HCC is up to four times more commonly diagnosed in males than in females (1, 25, 26)].”