Exercise and heart failure: A statement from the American Heart Association Committee on exercise, rehabilitation, and prevention.

By I. Piña, C. Apstein, G. Balady, R. Belardinelli, Bernard R. Chaitman, B. Duscha, B. Fletcher, J. Fleg, J. Myers, M. J. Sullivan. Circulation, 2003

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Pathophysiology of cardiac hypertrophy and heart failure: signaling pathways and novel therapeutic targets (2015, background): “Regular physical activity has been shown to improve the quality of life in patients with stable chronic HF, reverse pathological remodeling and improve heart function of patients with systolic HF, although patient non-adherence remains a major challenge (reviewed in De Maeyer et al. 2013; Piña et al”
2013 ACCF/AHA guideline for the management of heart failure: executive summary: a report of the American College of Cardiology Foundation/American Heart Association Task Force on practice guidelines. (2013, background): “Other benefits include improved endothelial function, blunted catecholamine spillover, increased peripheral oxygen extraction, and reduced hospital admission.(405,407,410,411) Many RCTs of exercise training in HF have been conducted, but the statistical power of most was low.”