Advantages of RGD peptides for directing cell association with biomaterials

By S. Bellis. Biomaterials, 2011

689 citations recorded by the source corpus.

Despite many years of in vitro research confirming the effectiveness of RGD in promoting cell attachment to a wide variety of biomaterials, animal studies evaluating tissue responses to implanted RGD-functionalized substrates have yielded more variable results The goals of this report are to present some of the reasons why cell culture studies may not always reliably predict in vivo responses, and more importantly, to highlight potential applications that may benefit from the use of RGD peptides.

Subfields: Biomedical Engineering, Cell Biology, Immunology and Allergy

View Paper: https://www.semanticscholar.org/paper/e749452ad2f94145815f4a1d660d2bce08104a9e

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Citations in the corpus

• 3D bioactive composite scaffolds for bone tissue engineering (2017, result): “Compared to pure PLGA nanofiber sheets, the initial adhesion and proliferation of cells were significantly enhanced on RGD-PLGA sheets, as found in other studies [201,202,334].”