Mature miR-184 as Potential Oncogenic microRNA of Squamous Cell Carcinoma of Tongue

By T. Wong, Xiao‐bing Liu, B. Wong, R. Ng, A. Yuen, W. Wei. Clinical Cancer Research, 2008

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Epigenetic regulation of miR-184 by MBD1 governs neural stem cell proliferation and differentiation (2010, neutral): “Altered miR-184 expression has been found in several types of tumors, although the proposed role of miR-184 in cell growth remains controversial (Chen and Stallings, 2007; Schaefer et al., 2009; Wong et al., 2008, 2009; Yu et al., 2008).”
MicroRNAs in body fluids—the mix of hormones and biomarkers (2011, neutral): “In patients with squamous-cell carcinoma of the tongue, plasma levels of miR-184 were significantly higher than those in healthy individuals and miR-184 levels were significantly reduced after surgical removal of the primary tumors”
Diagnostic and prognostic implications of microRNA profiling in prostate carcinoma (2009, result): “Hsa-miR-184 was strongly upregulated in lung carcinoma and its inhibition led to decreased cell proliferation.(35) In contrast, this miRNA was found to be strongly downregulated in MYCN-amplified tumors in comparison to other neuroblastoma subgroups.”
MicroRNA: Biogenesis, Function and Role in Cancer (2010, background): “One particular study showed specific reduction of miR-184 plasma levels following surgical resection of squamous cell carcinoma of the tongue [359].”