Src family kinases, key regulators of signal transduction

By S. Parsons, J. Parsons. Oncogene, 2004

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Optimized Hydrophobic Interactions and Hydrogen Bonding at the Target-Ligand Interface Leads the Pathways of Drug-Designing (2010, background): “Here, the hydrophobic –pocketassociated hot spot and hot regions between 4-amino substituted small molecules and the c-Src [24] and c-Abl [25] protein kinase, have been focused.”