Brain volume in first-episode schizophrenia

By R. G. Steen, Courtney Mull, R. Mcclure, Robert M. Hamer, Jeffrey A. Lieberman. British Journal of Psychiatry, 2006

804 citations recorded by the source corpus.

Subfields: Psychiatry and Mental health, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/e6f385d2de500e47d5d3301e64093b3371e9c0e2

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Psychiatry and Mental health

In Radiology, Nuclear Medicine and Imaging

Citations in the corpus

Dendritic spine pathology in neuropsychiatric disorders (2011, background): “Several studies have shown reductions in hippocampal volume and reduced spine density on subicular and CA3 dendrites in schizophreni”
Drosophila strategies to study psychiatric disorders. (2013, background): “Spine loss and volume decrease has been reported for the dorsolateral prefontral cortex, [68], the auditory cortex [154], and the hippocampus [91,151].”
Brain volume abnormalities in major depressive disorder: A meta‐analysis of magnetic resonance imaging studies (2009, result): “Although brain abnormalities have been identified in MDD, the number of neuroimaging studies in patients with this illness pale in comparison to those performed in schizophrenia (for metaanalyses see: [Boos et al., 2007; Honea et al., 2008; Steen et al., 2006; Wright et al., 2000]).”
Multi‐center machine learning in imaging psychiatry: A meta‐model approach (2017, positive): “Huge efforts to identify brain changes related to schizophrenia led to a large volume of magnetic resonance imaging (MRI) studies which reported a number of heterogeneous findings (Fusar-Poli et al., 2013; Haijma et al., 2013; Shepherd et al., 2012; Steen et al., 2006; van Erp et al., 2015).”
The anatomy of first-episode and chronic schizophrenia: an anatomical likelihood estimation meta-analysis. (2008, background): “The changes were more extensive than previously suggested by meta-analyses of region-of-interest studies that identified reduced whole brain volume and hippocampal volume and increased ventricular volume in first-episode schizophrenia (1, 2).”
Exercise as medicine – evidence for prescribing exercise as therapy in 26 different chronic diseases (2015, background): “Patients with schizophrenia are found to have a lower hippocampus volume compared to healthy people, a finding that may be significant for the pathogenesis of the chronic psychotic symptoms (Harrison, 2004; Steen et al., 2006).”
Brain-Derived Neurotrophic Factor and Neuropsychiatric Disorders (2012, background): “, 2007), particularly in the cortex and hippocampus (Steen et al., 2006).”